Explain the central dogma of molecular biology using your gene/protein/trait example.

EXPLAIN THE CENTRAL DOGMA OF MOLECULAR BIOLOGY USING YOUR GENE/PROTEIN/TRAIT EXAMPLE.

  1. Go to http://www.ncbi.nlm.nih.gov/gene
  2. You can either search for a human genetic disease or condition of your choice or you can chose from the list of examples below*. When searching for a disease or condition you may find multiple involved genes. I recommend clicking on the link to a few genes, read the summary and pick the one that is easiest to understand. You may also want to do a web-search to find additional (potentially easier to understand) information about your example. Please try to pick a disease/condition, or at least a gene, not yet described in the discussion by other students (post early if you want to research a specific condition).

*Examples: Huntingdon’s Disease, Muscular Dystrophy, Breast Cancer, Cystic Fibrosis, Albinism, Color Blindness, Parkinson’s Disease, Hemophilia, Sickle Cell Disease, Marfan Syndrome
3. Provide the following information for your specific example:
Name of Disease/Condition:
Name of Gene (pick one if there is multiple):
Type of mutation (s) identified in this gene:
Gene located on Chromosome #:
Name of Protein coded for by this gene:
Role of Protein:
Resulting Trait (symptoms) from mutation:
References used:
4. Explain the central dogma of molecular biology using your gene/protein/trait example.
Hint: When considering the role of this particular protein, does it make sense that a mutation in the gene that disrupts the production of the protein result in this particular trait? Or in other words, is there a clear connection between the role of the protein and the resulting trait?
Part II Punnett Square 

  • Pick one dominant or recessive trait found in your family (do a web-search for dominant/recessive human traits, keep in mind that most of our traits are notcontrolled in a simple dominant/recessive manner).
  • What is your phenotype for this trait? What is your likely genotype for this trait?  What is your parents/siblings and/or (if you have) children’s phenotypes for this trait?
  • Show a likely/potential Punnett Square for this trait in your family.
  • If you are adopted or otherwise do not know the phenotype of one or both of your parents for this trait, you can make up an example.

300 words

Do you think that DuBois’ concept of double consciousness still applies to racial/ethnic minorities today?

WHAT ARE THE ADVANTAGES AND LIMITATIONS OF EVOLUTIONARY THEORIES ROOTED IN BIOLOGY?

Before reading further you have to acces to the book by Jonathan H. Turner “Theoretical Sociology a Consise Introduction to Twevle Sociological Theories”
If you do not access to this book please do not bother asking to do this assignment. All of work have to come from that book plus i will attach some powerpoints.
 
1. Do you think that DuBois’ concept of double consciousness still applies to racial/ethnic minorities today? Why, or why not?
 
2. What are the strengths and limitations of structural functionalism?
 
3.What are the advantages and limitations of evolutionary theories rooted in biology?
 
 
4. Analyze one of your social roles (student, worker, parent, child, etc.) using a dramaturgical approach. Make sure to identify which theory you are using, and use various of its elements and/or propositions.
 
5. Use one of the models of conflict theory to explain the development of the “Occupy Wall Street” movement, and its failure. Make sure to identify the model you are using.
 
Additional instructions each question have to be 150-250 words no direct quotes form the book
 
The point is to show you understand each theory, in your own words, without distorting the theorists’ ideas.

Write a descriptive epidemiological analysis of the following diseases: Lyme disease or Malaria

Nursing homework help
 
Descriptive and Analytic Epidemiology
Required Reading
Boston University School of Public Health (n.d.). Overview of analytic studies. Retrieved from http://sphweb.bumc.bu.edu/otlt/MPH-Modules/EP/EP713_AnalyticOverview/EP713_AnalyticOverview_print.html
Carneiro, I. & Howard, N. (2011). Introduction to epidemiology (2nd ed). Open University Press: New York, NY. ISBN: 9780335244621
 
Centers for Disease Control and Prevention (CDC). (2012). Lesson 1: Introduction to Epidemiology, Section 6: Descriptive Epidemiology. Principles of epidemiology in public health practice (3rd ed.), pp. 1-31. U.S. Department of Health and Human Services, Office of Workforce and Career Development, Atlanta, GA. http://www.cdc.gov/ophss/csels/dsepd/ss1978/lesson1/section6.html
Centers for Disease Control and Prevention. (2014). E-learning course – Introduction to public health surveillance. Accessed from https://www.cdc.gov/publichealth101/documents/introduction-to-surveillance.pdf
Ellis-Christensen, T. (2016). What is descriptive epidemiology? Retrieved from: http://www.wisegeek.com/what-is-descriptive-epidemiology.htm
Optional Reading
Cosio G (2012). Epidemiological Overview of Tuberculosis [Presentation]. Retrieved from https://www.aphl.org/programs/infectious_disease/tuberculosis/TBCore/OverviewCourse.pdf
National Institute of Allergy and Infectious Diseases (2016). Malaria. Retrieved from http://www.niaid.nih.gov/topics/Malaria/research/Pages/biology.aspx
Homework Assignment
Case Assignment
This assignment has two parts.
Part 1: Write a descriptive epidemiological analysis of the following diseases: Lyme disease or Malaria. Describe the basic epidemiological patterns of this health condition by person, place, and time.
Part 2: You are a Health Officer for a rural county health department and have been assigned to study the frequency of an infectious disease such as tuberculosis or HIV/AIDS. Write an essay in which you do the following:
1. Describe observational and experimental epidemiology as the two (2) study designs apply to either of the diseases you have chosen. Be sure to identify differences between these two types of analytic epidemiology.
2. Under what conditions will you conduct a case-control study as opposed to a cohort study?
Be sure to support your opinion with evidence from the literature. Please research from the module materials and any credible, scholarly and professional source including the University’s online library in providing your response.
Length: 3-4 pages, excluding title page and references.
Assignment Expectations
Assessment and Grading: Your paper will be assessed based on the performance assessment rubric that is linked within the course. Review it before you begin working on the assignment.
Your work should also follow these Assignment Expectations.

Societal Aspects of Human Gene Editing.

Biology homework help
Topic 1. Societal Aspects of Human Gene Editing. Read the letter-to-the-editor to a newspaper by Dr. Cox, in which he states an opinion about the use of CRISPR for human gene editing.

  • (a) In your own words, what is the main point that Dr. Cox is trying to make?
  • (b) How can our society reconcile differing views about the ethics of using biotechnology? Explain.

Topic 2. Societal Aspects of Gene Drives in Wild Populations. In the article by Zimmer (2017), Kevin Esvelt says that he made a huge mistake by championing the application of a technology that he now says is far too dangerous to actually deploy. In a post of about 125 words, address the following:

  • (a) What is the technology that he championed? What does it consist of and why does he think it’s too risky to use outside the lab?
  • (b) In your opinion, what sorts of laws and regulations, if any, should society put into place to regulate the technology that Esvelt regrets championing?

Topic 3. Pedigrees for Traits that are Controlled by a Single Gene. While most human traits are controlled by more than one gene, a subset of them are controlled by a single gene for that trait. In such cases, the pedigree can be useful in determining the mode of inheritance, such as autosomal dominant, autosomalrecessive, or X-linked recessive. The document Pedigrees.pdf **  contains the pedigree for three different traits from the same family: Trait 1, Trait 2 and Trait 3. In each pedigree, individuals with the trait are shaded. These pedigrees follow the usual conventions for pedigrees: squares are males; circles are female; offspring are drawn under each mating pair. See book for details.

  • (a) Which of the three traits (Trait 1, Trait 2, Trait 3) follows an X-linked recessive pattern of inheritance?
  • (b) Which clues from the pedigree support your conclusion?

References
Cox, J. (2017, October 11). Compromise sure beats division. Courier-Record Newspaper [Blackstone, Virginia], p. A4. Can be found via this link:  cox crisprletter.pdf **
Zimmer, C. (2017, November 16). ‘Gene drives’ are too risky for field trials, scientists say. The New York Times. Retrieved from https://www.nytimes.com/2017/11/16/science/gene-drives-crispr.html?_r=0