HEMATOLOGY WORKSHEETS
MLSC-382A INSTRUCTOR: BETH RAWSON
1 Manual Diff Wksht Updated: 8/9/2020
MANUAL DIFFERENTIAL Worksheet STUDENT NAME: _____________________ Answer the following questions, referring to your clinical site’s policies and procedures as needed. 1. Given the accuracy of modern CBC analyzers, why are manual differentials and smear
reviews still performed at all? 2. List any WBC characteristics or inclusions reported as a part of the manual differential. NOTE:
This is not a listing of cell types. 3. Describe the process of quantifying RBC morphology.
4. Why are some RBC morphologic abnormalities noted as “Present” instead of with the semi- quantitative ranges (1+, 2+, 3+)?
5. List any platelet characteristics or abnormalities reported as part of the manual differential.
MLSC-382A INSTRUCTOR: BETH RAWSON
2 Manual Diff Wksht Updated: 8/9/2020
6. Why is it still sometimes necessary to perform manual WBC and platelet estimates from the stained peripheral blood smear?
7. What smear characteristics would make you suspect that the blood specimen is too
old/beyond the stated acceptable stability limits? 8. What is the process in place at your clinical site for responding to first time significant
abnormal findings for a patient? (For example, the finding of 75% blasts on the peripheral blood smear.)
