Explore how mitochondrial disease can occur at multiple levels in different mitochondrial processes
Explore how mitochondrial disease can occur at multiple levels in different mitochondrial processes by doing the following:
Explain what would hypothetically happen to the amount of ATP available to a cell if the entire Cori cycle were to occur and remain within a single cell (e.g., a muscle cell).
Identify specific numbers of ATP generated and used in the different parts of the cycle, in conjunction with your response from part B1.
Explain where in the CAC a hypothetical defect of an enzyme could occur that would decrease the overall ATP production of the mitochondria, including each of the following:
whether the entire cycle will continue to function
what will happen to the cycle products
why ATP production decreases
Note: This is a hypothetical defect, so the explanation should not include descriptions of any known disease.
Explain how a proton gradient is formed and used to make ATP during aerobic metabolism.
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